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In past Zika outbreaks, most people have not gotten sick, so people may not even know they are infected. Based on current knowledge, the greatest risk for complications from Zika is to a pregnant woman's fetus.

About 1 in 10 U.S. pregnant women with confirmed Zika had a fetus or baby with birth defects in 2016. Nearly 1,300 pregnant women with evidence of possible Zika infection were reported in 44 US states in 2016.